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KMID : 1143220200630010080
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Obstetrics & Gynecology Science
2020 Volume.63 No. 1 p.80 ~ p.86
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Influence of combined oral contraceptives on polycystic ovarian morphology-related parameters in Korean women with polycystic ovary syndrome
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Park Chan-Hong
Chun Sung-Wook
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Abstract
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Objective: This study aimed to assess the effect of combined oral contraceptives (COCs) on polycystic ovarian morphology (PCOM) and serum anti-Mullerian hormone (AMH) levels in Korean women with polycystic ovary syndrome (PCOS).
Methods: This university hospital study enrolled 36 Korean women who were newly diagnosed with PCOS based on the Rotterdam criteria and were treated with COCs for at least 1 year. We retrospectively evaluated the ovarian volume and number of antral follicles using ultrasonography and assessed serum AMH levels at baseline and after 1 year of COC treatment.
Results: Significant decreases in ovarian volume and antral follicle count were observed after 1 year of COC treatment. Compared to baseline, serum AMH levels were significantly decreased after 1 year.
Conclusion: COC treatment significantly affects ultrasound-assessed PCOM and serum AMH levels of patients with PCOS.
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KEYWORD
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Anti-Mullerian hormone, Combined oral contraceptives, Polycystic ovarian morphology, Polycystic ovary syndrome
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